کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3318549 1211607 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessment of the Severity of Acute Pancreatitis: No Room for Complacency
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
پیش نمایش صفحه اول مقاله
Assessment of the Severity of Acute Pancreatitis: No Room for Complacency
چکیده انگلیسی
Assessing the severity of acute pancreatitis is an important initial step in the management of these patients. An ideal prognostic system or marker does not exist, and current approaches fall short of what is needed when dealing with individual patients. It is recommended that the evaluation of the performance of a particular prognostic system or marker should include the calculation of positive and negative likelihood ratios, derived from a combination of sensitivity and specificity. Knowing the pre-test probability of a particular endpoint and the likelihood ratios make it possible to derive the post-test probability for the presence or absence of that endpoint for the individual patient in that population. The change in probability from before to after the test gives an indication of the clinical usefulness of the test. Improving the performance of prognostic systems and markers remains a challenge and there is no room for complacency. There are two ways forward: either the prognostic systems and markers need to be used in a more intelligent way, with combinations, sequencing or artificial neural network techniques, or by the discovery of new markers that measure critical aspects of outcome determining pathophysiology. No lack of energy has been expended on the latter, while the former offers more immediate promise.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pancreatology - Volume 8, Issue 2, May 2008, Pages 105-109
نویسندگان
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