کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
332682 | 545743 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Activation of extracellular signal-regulated kinase signaling by chronic electroconvulsive shock in the rat frontal cortex
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
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چکیده انگلیسی
The effects of chronic electroconvulsive shock (ECS), given daily for 1, 5 and 10 days, on the activation of extracellular signal-regulated kinase (ERK) were studied in the rat frontal cortex. The phosphorylation of MEK1/2 and ERK1/2 increased through 5 days of ECS. Thereafter, a plateau was achieved. The expression of brain-derived neurotrophic factor was continuously increased for 10 days. Our data show that the effect of ECS on ERK1/2 signaling is increased with chronic treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 145, Issue 1, 29 November 2006, Pages 75–78
Journal: Psychiatry Research - Volume 145, Issue 1, 29 November 2006, Pages 75–78
نویسندگان
Ung Gu Kang, Young Jin Koo, Won Je Jeon, Doo Byung Park, Yong Sung Juhnn, Joo Bae Park, Yong Sik Kim,