کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
332682 545743 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Activation of extracellular signal-regulated kinase signaling by chronic electroconvulsive shock in the rat frontal cortex
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Activation of extracellular signal-regulated kinase signaling by chronic electroconvulsive shock in the rat frontal cortex
چکیده انگلیسی

The effects of chronic electroconvulsive shock (ECS), given daily for 1, 5 and 10 days, on the activation of extracellular signal-regulated kinase (ERK) were studied in the rat frontal cortex. The phosphorylation of MEK1/2 and ERK1/2 increased through 5 days of ECS. Thereafter, a plateau was achieved. The expression of brain-derived neurotrophic factor was continuously increased for 10 days. Our data show that the effect of ECS on ERK1/2 signaling is increased with chronic treatment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 145, Issue 1, 29 November 2006, Pages 75–78
نویسندگان
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