Leczenie celowane w ostrych białaczkach szpikowych

Concerning other targets and agents the following appear important: blockers of CXCR4-SDF1 binding which is essential for AML blasts proliferation and survival (preliksafor, panobinostat, specyfic MoAb), agents influencing NF-κB (bortezomibe, parthenoide) and epigenetic drugs (azacytidine, decytabine).