کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3328560 1590720 2016 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Public health value of universal HPV vaccination
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Public health value of universal HPV vaccination
چکیده انگلیسی


• Human Papillomavirus vaccination demands urgent attention.
• The cost-effectiveness of including boys into HPV vaccination programs should be re-assessed.
• Steps must be taken to achieve the target of universal vaccination.
• There is sufficient evidence to urge the EU Community to eradicate all HPV related cancers.
• Policymakers must consider effective vaccination programs in the prevention of cancers.

BackgroundThe story of Human Papillomavirus vaccination demands reflection not only for its public health impact on the prophylactic management of HPV disease, but also for its relevant economic and social outcomes. Greater than ever data confirm the efficacy and support the urge for effective vaccination plans for both genders before sexual debut.MethodsA review of previous experience in gender-restricted vaccination programs has demonstrated a lower effectiveness. Limiting vaccination to women might increase the psychological burden on women by confirming a perceived inequality between genders; and even if all women were immunized, the HPV chain of transmission would still be maintained through men.ResultsThe cost-effectiveness of including boys into HPV vaccination programs should be re-assessed in view of the progressive drop of the economic burden of HPV-related diseases in men and women due to universal vaccination. The cost of the remarkable increase in anal and oropharyngeal HPV driven cancers in both sexes has been grossly underestimated or ignored.ConclusionsSteps must be taken by relevant bodies to achieve the target of universal vaccination. The analysis of HPV vaccination's clinical effectiveness vs. economic efficacy are supportive of the economic sustainability of vaccination programs both in women and men.In Europe, these achievements demand urgent attention to the social equity for both genders in healthcare. There is sufficient ethical, scientific, strategic and economic evidence to urge the European Community to develop and implement a coordinated and comprehensive strategy aimed at both genders and geographically balanced, to eradicate cervical cancer and other diseases caused by HPV in Europe.Policymakers must take into consideration effective vaccination programs in the prevention of cancers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 97, January 2016, Pages 157–167
نویسندگان
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