کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
332882 545783 2006 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Psychopathology in the young offspring of parents with bipolar disorder: A controlled pilot study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Psychopathology in the young offspring of parents with bipolar disorder: A controlled pilot study
چکیده انگلیسی

Studies have suggested that the offspring of parents with bipolar disorder are at risk for a spectrum of psychopathology, but few have focused on children in the youngest age ranges or examined the impact of comorbid parental disorders. We utilized a pre-existing sample of young (mean age: 6.8 years) offspring of parents with bipolar disorder (n = 34), of parents with panic or major depression (n = 179), and of parents with neither mood or anxiety disorder (n = 95). Children were assessed blindly to parental diagnoses using the Schedule for Affective Disorders and Schizophrenia-Epidemiologic version (K-SADS-E). Offspring of bipolar parents had significantly higher rates of disruptive behavior and anxiety disorders than offspring from both of the comparison groups, accounted for by elevated rates of ADHD and overanxious disorder. These comparisons were significant even when lifetime histories of the corresponding categories of comorbid disorders in the parents (disruptive behavior disorders and anxiety disorders) were covaried. In addition, offspring of bipolar parents had increased rates of bipolar I disorder, compared with psychiatric controls. Results support the hypotheses of elevated behavior, anxiety, and mood disorders among offspring at risk for bipolar disorder, and suggest that this psychopathology is already evident in early childhood.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 145, Issues 2–3, 7 December 2006, Pages 155–167
نویسندگان
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