کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3329399 1212394 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
MicroRNA and leukemia: Tiny molecule, great function
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
MicroRNA and leukemia: Tiny molecule, great function
چکیده انگلیسی

MicroRNAs are small noncoding RNA molecules that negatively regulate gene expression via degradation or translational repression of their targeted messenger RNAs (mRNAs). It is known that aberrant microRNA expression can play a vital role in the pathology of leukemia, thus microRNAs have rapidly emerged as potential targets for therapeutics. This review focuses on recent researches on the important roles of microRNAs in the pathogenesis of leukemia, including acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL).

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 74, Issue 3, June 2010, Pages 149–155
نویسندگان
, , , , ,