Hodgkin's Lymphoma: The Role of Radiation in the Modern Combined Strategies of Treatment

A history of the treatment of Hodgkin's disease with radiation therapy and chemotherapy is presented. Studies are reviewed examining treatment for favorable and unfavorable presentation of stage I–II disease, stage III–IV disease, and relapsed disease. In this era of combined-modality therapy we have reached the point of near-total conquest of Hodgkin's lymphoma, but challenges remain. Directions for future research are discussed.