کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3331708 | 1590858 | 2010 | 29 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Acute Myeloid Leukemia
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
هماتولوژی
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چکیده انگلیسی
Acute myeloid leukemia (AML) is a heterogeneous group of leukemias that result from clonal transformation of hematopoietic precursors through the acquisition of chromosomal rearrangements and multiple gene mutations. As a result of highly collaborative clinical research by pediatric cooperative cancer groups worldwide, disease-free survival has improved significantly during the past 3 decades. Further improvements in outcomes of children who have AML probably will reflect continued progress in understanding the biology of AML and the concomitant development of new molecularly targeted agents for use in combination with conventional chemotherapy drugs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hematology/Oncology Clinics of North America - Volume 24, Issue 1, February 2010, Pages 35–63
Journal: Hematology/Oncology Clinics of North America - Volume 24, Issue 1, February 2010, Pages 35–63
نویسندگان
Jeffrey E. Rubnitz, Brenda Gibson, Franklin O. Smith,