کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3334307 1213436 2016 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comprehensive Assessment and Classification of High-Grade B-cell Lymphomas
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Comprehensive Assessment and Classification of High-Grade B-cell Lymphomas
چکیده انگلیسی

High-grade B-cell lymphomas (HGBCLs) are a heterogeneous group of neoplasms that include subsets of diffuse large B-cell lymphoma, Burkitt lymphoma, and lymphomas with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. Morphologically indistinguishable HGBCLs may demonstrate variable clinical courses and responses to therapy. The morphologic evaluation and classification of these neoplasms must be followed by further genetic and immunophenotypic work-up. These additional diagnostic modalities lead to a comprehensive stratification of HGBCL that determines the prognosis and optimal therapy. This article reviews the well-established and emerging biomarkers that are most relevant to the clinical management of HGBCL.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Pathology Clinics - Volume 9, Issue 1, March 2016, Pages 41–54
نویسندگان
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