کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3336179 1213561 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Haemolytic disease of fetus and newborn caused by ABO antibodies in a cisAB offspring
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Haemolytic disease of fetus and newborn caused by ABO antibodies in a cisAB offspring
چکیده انگلیسی

ABO hemolytic disease of fetus and newborn (ABO-HDFN) occurs almost exclusively in infants of blood group A or B who are born to group O mothers because IgG anti-A or -B occurs more commonly in group O than in group A or B individuals. We report a case of clinically significant ABO-HDFN where the mother was blood group O with elevated IgG anti-A and anti-B titers and delivered a child with an A2B phenotype. This unusual ABO constellation between mother and infant was based on the inheritance of a rare ABO allele encoding for a glycosyltransferase capable of synthesizing both A and B antigens. Because both anti-A and anti-B antibodies may have been involved in hemolysis in this case, it may be relevant to consider the cisAB phenomenon when monitoring ABO-incompatible pregnancies and births.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transfusion and Apheresis Science - Volume 39, Issue 2, October 2008, Pages 123–128
نویسندگان
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