کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
333850 545979 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Plasma levels of lipoprotein (a) in patients with major depressive disorders
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Plasma levels of lipoprotein (a) in patients with major depressive disorders
چکیده انگلیسی

Depression and cardiovascular disease are among the most prevalent health problems. The evidence that depression is a risk factor for the development and progression of coronary heart disease has strengthened over the past several years, but the exact reasons are not yet clear. Elevated lipoprotein (a) (Lp(a)) concentrations seem to be the major factor for the progression of the atherosclerosis and coronary heart disease. In this study, we measured the plasma levels of Lp(a) in 35 patients with major depressive disorder and 35 healthy controls. The two groups were matched by age and gender. Lp(a) measurement was performed using an immunoturbidimetric method. Total cholesterol was significantly lower in the patient group (mean ± SD: 144.65 ± 22.13 vs. 186.14 ± 34.48 mg/dl. The Lp(a) levels of the patient group differed significantly from control values. Patients with major depressive disorder had higher plasma levels of Lp(a) than healthy controls (34.94 ± 18.01 vs. 20.08 ± 11.27 mg/dl). The results of the present study suggest that the increase of Lp(a) may contribute to higher cardiovascular risk in patients with major depressive disorder.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 169, Issue 3, 30 October 2009, Pages 253–256
نویسندگان
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