کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3342288 | 1214276 | 2009 | 6 صفحه PDF | دانلود رایگان |
BackgroundThis review aims to make laboratory professionals and clinicians more familiar with the basic concepts that deal with the clinical performance characteristics of a laboratory test.ContentBasic measures of the clinical performance characteristics of a laboratory test, such as sensitivity, specificity, likelihoods, likelihood ratio, post-test probability, odds, Bayes theorem, and receiver–operator characteristic curve are explained. The concepts are illustrated with examples (anti-CCP antibodies) that are worked out in a spreadsheet.SummaryThis review seeks to provide laboratory professionals and clinicians with a better understanding of the clinical performance characteristics of a laboratory test and of evidence-based laboratory medicine. The manuscript emphasizes a strong link between clinical statistics and evidence-based laboratory medicine.
Journal: Autoimmunity Reviews - Volume 8, Issue 7, June 2009, Pages 543–548