کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3342402 1214284 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Allergy and autoimmunity: Parallels and dissimilarity: The Yin and Yang of Immunopathology
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Allergy and autoimmunity: Parallels and dissimilarity: The Yin and Yang of Immunopathology
چکیده انگلیسی

The etiopathogenesis of allergy and autoimmune diseases is caused by genetic and acquired (environmental) factors, which might be common to both immnunopathologies. Genetic factors play an important role in the development and process of immunopathological diseases. Several studies suggest a close relation between gene polymorphism of HLA and cytokines and development of autoimmunity and allergy. Certain gene polymorphisms act as risk or as protective factors. The infection also plays an important role in the induction of allergy and autoimmunity — as a trigger or as a protective factor. Moreover, similar clinical manifestations of both immunopathologies could result in diagnostic problems. This review summarizes the linkage of mechanisms of etiopathogenesis, clinical manifestations and therapeutic strategy between allergic and autoimmune diseases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 8, Issue 4, February 2009, Pages 302–308
نویسندگان
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