کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3342730 1214306 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interleukin-18 in chronic joint diseases
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Interleukin-18 in chronic joint diseases
چکیده انگلیسی

Interleukin-18 is a cytokine member of the IL-1 super family that seems to exert powerful Th1-promoting activities in synergy with IL-12. Here we describe the participation of IL-18 in inflammatory joint diseases, in particular rheumatoid arthritis, adult onset Still's disease and juvenile idiopathic arthritis. The emphasis of this study was to summarize in vivo and in vitro studies that focused the action of this pro-inflammatory cytokine on the arthritic process as well as its role in the complex network of chemical mediators involved.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 6, Issue 4, March 2007, Pages 253–256
نویسندگان
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