کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3393804 1592791 2014 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Leishmaniases in Maghreb: An endemic neglected disease
ترجمه فارسی عنوان
لیشمانیوز در مغرب: یک بیماری غیرمستقیم اندمیک
کلمات کلیدی
لیشمانیا، مغرب، لیشمانیا تاکسون، پلی مورفیسم آنزیمی، توزیع جغرافیایی، چرخه انتقال
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
چکیده انگلیسی


• Maghreb is an endemic area for both visceral and cutaneous leishmaniasis.
• Cutaneous leishmaniasis in Maghreb is caused by four taxa.
• L. major is the most widespread taxon and L. tropica is the most polymorphic one.
• Visceral leishmaniasis is caused by six zymodemes of the L. infantum taxon.
• Leishmaniases control strategies are still rare and most of them are not well applied.

Maghreb is known to be one of the most endemic areas of leishmaniases where both visceral and cutaneous forms are reported. Cutaneous leishmaniasis (CL) is older and has a higher prevalence than visceral one (VL). It is caused by four taxa (Leishmania (L.) major, L. infantum, L. tropica and L. killicki) which are responsible for a large clinical spectrum of lesions. Most transmission cycles of these taxa are known and many phlebotomine sandflies vectors and reservoir hosts are identified. The zoonotic transmission is well established for L. major. However, for L. infantum and L. killicki it needs more investigations to be proven. Regarding L. tropica, studies suggest it to be of both zoonotic and anthroponotic types. The isoenzymatic characterization of these four taxa showed a large enzymatic polymorphism varying from two zymodemes for L. major to 10 zymodemes for L. tropica. Cutaneous leishmaniasis is widely distributed and covers all bioclimatic stages with the coexistence of more than one taxon in the same foci.Visceral leishmaniasis is the second form of leishmaniases in Maghreb. Only L. infantum is known to cause this disease. The transmission cycle of this parasite is zoonotic but still not well known. The isoenzymatic identification of L. infantum causing VL showed the presence of six zymodemes. Geographically, VL is distributed in all bioclimatic stages of Maghreb countries.Despite all the previous studies realized on leishmaniases in Maghreb, they are still considered as neglected diseases because of the rarity or the absence of efficient control strategies.

Leishmaniases in Maghreb are still neglected diseases. Their incidence and geographical spread are increasing because of the environmental changes and the absence of efficient control strategies.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Tropica - Volume 132, April 2014, Pages 80–93
نویسندگان
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