کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3394221 1221454 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Efficacy of bioactive compounds from Curcuma aromatica against mosquito larvae
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Efficacy of bioactive compounds from Curcuma aromatica against mosquito larvae
چکیده انگلیسی

With the development of resistance to conventionally used synthetic insecticides, vector management has become acutely problematic. Hence more attention has been focused on botanicals. Therefore our present study was aimed to evaluate the efficacy of extracts from rhizomes of Curcuma aromatica against the larvae of filariasis vector mosquitoes, Culex quinquefasciatus employing standard WHO procedure at Mysore. The soxhlet extraction was carried out using non-polar organic solvent, petroleum ether. The efficacy of petroleum ether extract seemed to be effective with LC50 and LC90 values of 11.42 and 18.00 ppm respectively. Bioassay-guided fractionation through flash chromatography lead to the isolation of two larvicidal compounds namely 9-oxoneoprocurcumenol and neoprocurcumenol. Between the two, 9-oxoneoprocurcumenol exerted significant toxicity (P < 0.01) on mosquito larvae with LC50 value of 5.81 ppm and LC90 being 9.99 ppm compared to neoprocurcumenol with 13.69 and 23.92 ppm of LC50 and LC90 values respectively. From the results, C. aromatica could be considered as one of the powerful candidate to bring about useful botanicals so as to prevent the resurgence of mosquito vectors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Tropica - Volume 113, Issue 1, January 2010, Pages 7–11
نویسندگان
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