کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3397029 1222210 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecular and immunohistochemical detection of rotavirus in urinary sediment cells of children with rotavirus gastroenteritis
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Molecular and immunohistochemical detection of rotavirus in urinary sediment cells of children with rotavirus gastroenteritis
چکیده انگلیسی

This is the first report showing that rotavirus infects the urinary sediment cells in immunocompetent children with rotavirus gastroenteritis. We found that inclusion-bearing cells were frequently detected in the urine samples of patients with rotavirus gastroenteritis. These cells were positive for cytokeratin, which was sometimes coexpressed with rotavirus antigen, in our immunohistochemical analysis. Moreover, in nested RT-PCR experiments, we detected rotavirus double-stranded RNA in some urine samples of patients with rotavirus gastroenteritis. We concluded that rotavirus could lead to infection of the urinary sediment cells concomitantly with rotavirus gastroenteritis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Microbiology and Infection - Volume 17, Issue 8, August 2011, Pages 1190–1193
نویسندگان
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