کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3397150 | 1222216 | 2011 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Chorioamnionitis: from pathogenesis to treatment Chorioamnionitis: from pathogenesis to treatment](/preview/png/3397150.png)
Chorioamnionitis refers to inflammation of the amniochorionic membrane, and is a significant cause of maternal and neonatal morbidity. Chorioamnionitis most often occurs as a result of ascending infection, and is commonly associated with premature rupture of the membranes. Chorioamnionitis is generally the result of a polymicrobial infection, with Ureaplasma urealyticum, Mycoplasma hominis and Gramnegative anaerobes being frequent causative organisms. The mainstay of treatment includes antimicrobial agents, antipyretics, expedition of delivery and supportive care. Further research is required to identify mechanistic pathways and early biomarkers that accurately predict women at higher risk of adverse maternal and neonatal outcomes, and that can thus lead to the development of additional treatment and prevention strategies.
Journal: Clinical Microbiology and Infection - Volume 17, Issue 9, September 2011, Pages 1304–1311