کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3397816 1222250 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Global regulators and environmental adaptation in Gram-negative pathogens
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Global regulators and environmental adaptation in Gram-negative pathogens
چکیده انگلیسی

A powerful combination of single-gene studies and whole genome approaches has provided a wealth of information about the regulatory circuits used by bacteria to adapt to the environmental changes that are encountered during infection. The facultative intracellular pathogen Salmonella enterica will be used to illustrate how global regulators such as the nucleoid-associated proteins Fis and H-NS collaborate with fluctuations in the superhelicity of the DNA template to modify the gene expression profile of the bacterial cell outside and inside the host.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Microbiology and Infection - Volume 15, Supplement 1, January 2009, Pages 47–50
نویسندگان
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