کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3399400 | 1222518 | 2010 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Non-mammalian animal models to study infectious disease: worms or fly fishing?
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A major challenge in studying human infectious diseases is to understand in detail the molecular bases, including both pathogen and host-related factors, which contribute to disease development. Non-mammalian models have proven to be of great value for our understanding of disease and have shown conservation in fundamental virulence mechanisms for the infection of evolutionary divergent hosts. In this review we describe recent advances with three major non-mammalian models used for analysis of infectious disease in humans; the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and the zebrafish Danio rerio.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Microbiology - Volume 13, Issue 1, February 2010, Pages 79–85
Journal: Current Opinion in Microbiology - Volume 13, Issue 1, February 2010, Pages 79–85
نویسندگان
David O’Callaghan, Annette Vergunst,