کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3399453 | 1222522 | 2009 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Chasing the treasures of the sea — bacterial marine natural products
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Bacterial marine natural products are an important source of novel lead structures for drug discovery. The cytotoxic properties of many of these secondary metabolites are of particular interest for the development of new anticancer agents. Tremendous advances in marine molecular biology, genome sequencing, and bioinformatics have paved the way to fully exploit the biomedical potential of marine bacterial products. In addition, unique biosynthetic enzymes discovered from bacteria from the sea have begun to emerge as powerful biocatalysts in medicinal chemistry and total synthesis. The increasingly interdisciplinary field of marine natural product chemistry thus strongly impacts future developments in medicine, chemistry, and biology.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Microbiology - Volume 12, Issue 3, June 2009, Pages 252–260
Journal: Current Opinion in Microbiology - Volume 12, Issue 3, June 2009, Pages 252–260
نویسندگان
Tobias AM Gulder, Bradley S Moore,