کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3400086 1593065 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers
ترجمه فارسی عنوان
استئوپنتین در بیماری مزمن انسدادی ریه: افراد سیگاری و سابق سیگاری
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های عفونی
چکیده انگلیسی

BackgroundCOPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified.ObjectivesTo study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients.MethodsSerum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits.ResultsThere was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation.ConclusionSerum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Egyptian Journal of Chest Diseases and Tuberculosis - Volume 64, Issue 1, January 2015, Pages 63–66
نویسندگان
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