Coproantigen capture ELISA for detection of Clonorchis sinensis infection in experimentally infected rats

► Development of ELISA for detection of C. sinensis antigens (CsAg) in feces of rats. ► Early detection of CsAg in feces by ELISA before detection of eggs. ► Positive correlations between the fecal CsAg and both EPG and worm burden. ► The coproantigen capture ELISA may be useful for mass screening in endemic areas.