کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3421856 1226691 2015 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Positioning of bacterial chemoreceptors
ترجمه فارسی عنوان
موقعیت شیمی درمانی باکتریایی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
چکیده انگلیسی


• Bacteria organise their chemosensory proteins into large hexagonal arrays, which can be either transmembrane or soluble.
• Chemosensory arrays display a wide variety of positioning patterns within the cell.
• Often these positioning patterns are created by mechanisms evolved to ensure the equal segregation of arrays between daughter cells on cell division.
• Mechanisms discovered include stochastic self-assembly, cellular landmarks, and ParA protiens.

For optimum growth, bacteria must adapt to their environment, and one way that many species do this is by moving towards favourable conditions. To do so requires mechanisms to both physically drive movement and provide directionality to this movement. The pathways that control this directionality comprise chemoreceptors, which, along with an adaptor protein (CheW) and kinase (CheA), form large hexagonal arrays. These arrays can be formed around transmembrane receptors, resulting in arrays embedded in the inner membrane, or they can comprise soluble receptors, forming arrays in the cytoplasm. Across bacterial species, chemoreceptor arrays (both transmembrane and soluble) are localised to a variety of positions within the cell; some species with multiple arrays demonstrate this variety within individual cells. In many cases, the positioning pattern of the arrays is linked to the need for segregation of arrays between daughter cells on division, ensuring the production of chemotactically competent progeny. Multiple mechanisms have evolved to drive this segregation, including stochastic self-assembly, cellular landmarks, and the utilisation of ParA homologues. The variety of mechanisms highlights the importance of chemotaxis to motile species.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 23, Issue 5, May 2015, Pages 247–256
نویسندگان
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