کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3421991 1226708 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
HTLV-1 infection: what determines the risk of inflammatory disease?
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
HTLV-1 infection: what determines the risk of inflammatory disease?
چکیده انگلیسی

Human T-lymphotropic virus type 1 (HTLV-1) is an exogenous retrovirus that persists lifelong in the infected host. Infection has been linked to a spectrum of diverse diseases: adult T cell leukemia, encephalomyelopathy, and predisposition to opportunistic bacterial and helminth infections. Applications of new technologies and biological concepts to the field have provided new insights into viral persistence and pathogenesis in HTLV-1 infection. Here, we summarize the emerging concepts of dynamic HTLV-1–host interactions and propose that chronic interferon (IFN) production causes tissue damage in HTLV-1-associated inflammatory diseases.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 20, Issue 10, October 2012, Pages 494–500
نویسندگان
, ,