کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3422104 1226720 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria
چکیده انگلیسی

Many pathogenic bacteria use cell–cell signaling to regulate the expression of factors contributing to virulence. Bacteria produce signals of diverse structural classes. The signal molecule known as diffusible signal factor (DSF) is a cis-unsaturated fatty acid that was first described in the plant pathogen Xanthomonas campestris. Recent work has shown that structurally related molecules produced by the unrelated bacteria Burkholderia cenocepacia and Pseudomonas aeruginosa regulate virulence, biofilm formation and antibiotic tolerance in these important human pathogens. Furthermore, DSF family signals have been shown to be involved in interspecies signaling that modulates bacterial behavior. An understanding of these diverse signaling mechanisms could suggest strategies for interference, with consequences for disease control.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 19, Issue 3, March 2011, Pages 145–152
نویسندگان
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