کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3422250 1226736 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Structure and mechanism of energy-coupling factor transporters
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Structure and mechanism of energy-coupling factor transporters
چکیده انگلیسی


• The interactions and arrangement of the energy-coupling factor (ECF) transporter complex are discussed.
• The structural fold and the substrate binding site of the EcfS proteins are compared.
• Energy coupling and a working model of ECF transporters are proposed.

Energy-coupling factor (ECF) transporters form a new family of ATP-binding cassette (ABC) transporters and are widely used by prokaryotes to take up micronutrients from the environment. Instead of using the periplasmic solute-binding proteins (SBPs), ECF transporters use the membrane S proteins for substrate capture and translocation. In this review, we will focus on structural advances that have been made regarding how substrates are recognized by ECF transporters and possible transport mechanisms employed by the ECF transporters.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 21, Issue 12, December 2013, Pages 652–659
نویسندگان
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