کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3422480 1226762 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modulation of stress and virulence in Listeria monocytogenes
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Modulation of stress and virulence in Listeria monocytogenes
چکیده انگلیسی

Listeria monocytogenes can respond rapidly to changing environmental conditions, as illustrated by its ability to transition from a saprophyte to an orally transmitted facultative intracellular pathogen. Differential associations between various alternative σ factors and a core RNA polymerase provide a transcriptional mechanism for regulating bacterial gene expression that is crucial for survival in rapidly changing conditions. Alternative σ factors are key components of complex L. monocytogenes regulatory networks that include multiple transcriptional regulators of stress-response and virulence genes, regulation of genes encoding other regulators, and regulation of small RNAs. In this article, the contributions of various σ factors to L. monocytogenes stress response and virulence are described.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 16, Issue 8, August 2008, Pages 388–396
نویسندگان
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