کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3423702 1227059 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Unravelling the moulting degradome: new opportunities for chemotherapy?
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Unravelling the moulting degradome: new opportunities for chemotherapy?
چکیده انگلیسی

Replacement of the nematode cuticle with a newly synthesized cuticle (a process known as moulting) occurs four times during larval development. Therefore, the key components of this essential developmental process represent attractive targets for new chemotherapeutic strategies. Recent advances in understanding the molecular genetics of nematode moulting should stimulate and facilitate development of novel drugs that target the essential molecules of the moulting cycle. In particular, we argue that further understanding of the moulting degradome and its key peptidase members offers an important opportunity for the development of novel antinematode agents.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 23, Issue 6, June 2007, Pages 248–253
نویسندگان
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