کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3423707 1227059 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Transmission consequences of coinfection: cytokines writ large?
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Transmission consequences of coinfection: cytokines writ large?
چکیده انگلیسی

Coinfection of a host by multiple parasite species is commonly observed and recent epidemiological work indicates that coinfection can enhance parasite transmission. This article proposes an immunoepidemiological framework to understand how within-host interactions during coinfection might affect between-host transmission. Cytokines, immune signalling molecules with a fundamental role in the amplification of antiparasitic effector mechanisms, provide a useful way to simplify immunological complexity for this endeavour – focusing on cytokines offers analytical tractability without sacrificing realism. Testable predictions about the epidemiological consequences of coinfection are generated by this conceptual framework.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 23, Issue 6, June 2007, Pages 284–291
نویسندگان
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