کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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342376 | 548816 | 2009 | 4 صفحه PDF | دانلود رایگان |
Purpose and methodsMigraine, with or without aura, affects from 10% to 14% of the population, and is as such one of the most common headache disorders. A unified hypothesis for the physiopathology of migraine and its relationship with epileptic migraine and migralepsy has yet to be formulated.Trigemino-vascular system (TVS) activation is believed to play a crucial role in the “pain phase” in migraine; cortical spreading depression (CSD) is considered to be the primary cause of TVS activation.On the basis of data in the literature, I would like to stress that TVS activation may originate at different cortical and subcortical levels. For example, as recently reported, an epileptic focus, originating and propagating along cortical non-eloquent/silent areas, through CSD, rarely causes TVS activation with migraine as the sole ictal epileptic manifestation.Results and conclusionThe multiple considerations that arise from this hypothesis, including the under-diagnosed ictal epileptic headache, are discussed; EEG (ictal and inter-ictal) recording with intermittent photic stimulation (IPS), according to the standardized international protocol, is strongly recommended in selected migraine populations.
Journal: Seizure - Volume 18, Issue 5, June 2009, Pages 309–312