کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
342435 548822 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patients with epilepsy are at an increased risk of subsequent stroke: A population-based cohort study
ترجمه فارسی عنوان
بیماران مبتلا به صرع در معرض خطر افزایش سکته مغزی هستند: یک مطالعه کوهورت مبتنی بر جمعیت
کلمات کلیدی
همبودی، وجود همزمان دو بیماری، صرع، سکته مغزی ادعای بیمه، مطالعه کوهورت مجدد
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی

PurposeEpilepsy is well known as a disorder in poststroke patients. However, studies that have investigated the association between epilepsy and the risk of subsequent stroke are limited. This population-based study investigated the incidence and risk of stroke in patients with epilepsy by using the Taiwan National Health Insurance claims data.MethodsWe identified 3812 patients newly diagnosed with epilepsy in 2000–2008 and 15,248 nonepilepsy comparisons frequency matched according to sex, age, and index year. We searched for subsequent stroke diagnoses in both cohorts until the end of 2009. The incidence rates and hazard ratios of stroke were estimated based on sex, age, the average defined daily doses (DDDs) of antiepilepsy drugs, and comorbidity.ResultsThe stroke incidence of the epilepsy cohort was 3-fold higher than that of the comparison cohort. The age-specific results indicated that in the epilepsy cohort and the comparison cohort, the risk was the highest for the youngest group (20–39 years).ConclusionThe patients with epilepsy exhibited a higher incidence of cerebral stroke than the general population did. In addition, younger patients with epilepsy and patients who took a high doses of antiepileptic drugs exhibited a high risk of stroke.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seizure - Volume 23, Issue 5, May 2014, Pages 377–381
نویسندگان
, , , , , ,