کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3428724 | 1594384 | 2012 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Structural insights into the classification of Mud Crab Reovirus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ویروس شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Cryo-electron microscopy was applied to analyze mud crab reovirus (MCRV), which causes ‘sleeping disease’ in mud crab, Scylla serrata, a marine species cultured in China. We present here the three dimensional structure of MCRV at 13.8 Å resolution. The outer capsid shell is composed of 260 trimers with complete T = 13 icosahedral symmetry. A major difference between MCRV and previously reported aquareoviruses is that it lacks a pentameric turret structure. These results together with recently published molecular biological evidence (Deng et al., 2012) indicate that, from a structural perspective, MCRV should be classified as a new member of the family Reoviridae.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virus Research - Volume 166, Issues 1–2, June 2012, Pages 116–120
Journal: Virus Research - Volume 166, Issues 1–2, June 2012, Pages 116–120
نویسندگان
Zengwei Huang, Xiexiong Deng, Yinyin Li, Hongjun Su, Kunpeng Li, Zhixun Guo, Peirui Zheng, Haidong Xu, Jianguo He, Qinfen Zhang, Shaoping Weng,