کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3430594 1228278 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genetic analysis of Dengue virus type 3 isolated in Buenos Aires, Argentina
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ویروس شناسی
پیش نمایش صفحه اول مقاله
Genetic analysis of Dengue virus type 3 isolated in Buenos Aires, Argentina
چکیده انگلیسی

Dengue virus as a member of mosquito-borne flaviviruses is responsible for an increasing number of human infections worldwide, mainly in tropical and subtropical urban areas. The agent, a single-stranded positive sense RNA virus, is comprised of four serotypes and genetic variation within each serotype can be further divided into different genotypes. Dengue outbreaks were reported in bordering countries during the last years; the latest reported in Paraguay in 2006–2007. In Buenos Aires, 32 dengue cases were confirmed in travelers coming from this country by anti-dengue IgM antibodies detection, RT-PCR and/or isolation in C6/36 cell line. Structural proteins C, prM/M, E and non-structural proteins 1 and 2 from eight viruses were genetically characterized. Phylogenetic inference was performed for the E-protein and all viruses clustered with dengue virus 3 Genotype III. This is the first report of genetic characterization of dengue virus 3 in Argentina.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Virus Research - Volume 135, Issue 1, July 2008, Pages 83–88
نویسندگان
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