کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3430679 | 1594402 | 2007 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Detection of intersubtype recombinants with respect to env and nef genes of HIV-1 among female sex workers in Calcutta, India Detection of intersubtype recombinants with respect to env and nef genes of HIV-1 among female sex workers in Calcutta, India](/preview/png/3430679.png)
HIV-1 detected among female sex workers in Calcutta, India was characterized in respect to env and nef genes. A total of 39 HIV-1 seropositive samples were used in the study. Phylogenetic analysis of the nucleotide sequences of respective regions showed that 22 out of 39 samples (56.4%) were infected with subtype C with respect to both env and nef genes; however, 17 samples (43.6%) showed distinct subtype discordance. Simplot analysis of these samples showed the presence of intersubtype recombination between subtypes C and B. Both env C/nef B and env B/nef C recombinants were found to be present; 16 samples were found to be env C/nef B and 1 sample was detected as env B/nef C. This result indicates the emergence of intersubtype recombinants of HIV-1 for the first time in this eastern part of India.
Journal: Virus Research - Volume 130, Issues 1–2, December 2007, Pages 310–314