Defining characteristics for young children meeting cutoff on the modified checklist for autism in toddlers

Early diagnosis of Autism Spectrum Disorders (ASDs) is crucial so that early intervention services, which have been found to best alleviate symptoms of ASD in children, can be implemented. Currently, the Modified Checklist for Autism in Toddlers (M-CHAT) and the Baby and Infant Screen for Children with aUtIsm Traits-Part 1 (BISCUIT-Part 1) are the most widely researched ASD measures in early childhood. However, the M-CHAT provides many false positive results as it is solely used as a screening instrument as opposed to a diagnostic measure, while the BISCUIT-Part 1 appears to have more diagnostic fidelity. The current study examined 243 toddlers who failed the M-CHAT screener and were therefore referred for further evaluation. Upon further evaluation, 141 of the toddlers were diagnosed with an ASD while the remaining 102 were not. Characteristics differentiating these two groups on the M-CHAT, BISCUIT-Part 1, and Battelle Developmental Inventory, Second Edition (BDI-II) were examined with analyses supporting the hypotheses that children in the ASD group had higher M-CHAT and BISCUIT-Part 1 scores in conjunction with lower BDI-II scores. Based on these results, the incremental predictive validity of the M-CHAT was assessed; the BISCUIT-Part 1 was found to be more accurate in arriving at ASD diagnoses. The implications of these findings are discussed.

► M-CHAT and the BISCUIT are used to screen young children for ASD.
► Failing M-CHAT with later ASD diagnoses scored higher on M-CHAT and BISCUIT; lower scores for BDI-2.
► BISCUIT-Part 1 is more accurate for ASD diagnoses.