کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3966090 | 1600756 | 2015 | 5 صفحه PDF | دانلود رایگان |
Objective: Intrauterine insemination (IUI) is a simple procedure which has been used to treat unexplained infertility. There is no agreement about the optimum time for IUI. An interval of only a few hours exists in which it can be performed. The aim of this study was to find out whether there is a difference in pregnancy rate if IUI is performed 48 h rather than later than 36 h after Human chorionic gonadotropin (hCG) Injection. Setting: infertility clinic, Kasr Alainy, Cairo University Hospital. Materials and methods: A randomized case-control prospective study in which subjects in Group A will perform IUI 48 h after hCG injection after controlled ovarian stimulation, in comparison with Group B (control) in which the IUI will be performed 36 h after hCG injection. Main outcome measures: Pregnancy rate in group A was 22.6% while group B was 10.6% (p = 0.049). The mean Number of mature follicles in group A was 2.6 ± 1 follicles, while that of group B was 2.1 ± 0.9 follicles (p = 0.002). Conclusions: A lot of controversy surrounds the correct timing of IUI. Our study showed a statistically significant increase in pregnancy rate up to 22.6% in patients performing IUI 48 h after hCG trigger, compared to the 10.6% in the patients having the procedure done 12 h earlier.
Journal: Middle East Fertility Society Journal - Volume 20, Issue 4, December 2015, Pages 290–294