کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3979159 1257322 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chimiothérapie intensive et autogreffe de cellules souches hématopoïétiques dans les tumeurs germinales
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Chimiothérapie intensive et autogreffe de cellules souches hématopoïétiques dans les tumeurs germinales
چکیده انگلیسی
Germ cell tumors are cured by cisplatin-based chemotherapy and secondary surgery. Patients with initial poor response to chemotherapy and relapsed disease patients have poor prognosis. Among different therapeutic approaches high dose chemotherapy with hematopoietic stem cell support has been studied. Despite the existence of a number of phase II trials and several well-conducted phase III trials, this approach is neither a standard nor an option in the setting of first line and first salvage treatment. A randomized phase III trial has recently been initiated and patients with relapsed disease should be offered to participate in the trial. Several selected indications could be discussed in further lines of treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bulletin du Cancer - Volume 98, Issue 8, August 2011, Pages 945-949
نویسندگان
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