کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3980699 | 1257451 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Recurrent disease four years after surgery and adjuvant chemotherapy
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
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چکیده انگلیسی
A 71-year-old man with previous primary resection was found to have extensive liver metastases. Chemotherapy was initiated with FOLFIRI plus bevacizumab, in hopes of reducing the hepatic tumor burden; this resulted in manageable toxicity and was sufficiently effective to allow resection. After 6 weeks, 6 cycles of chemotherapy with FOLFIRI plus bevacizumab were administered; the patient was free of new lesions for the next 19 months. Readministration of FOLFIRI plus bevacizumab resulted in minor response and symptom control for another 9 months before further progression was observed. The subsequent administration of FOLFOX for 8 cycles and FOLFIRI plus cetuximab were unable to prevent further decline. Detailed explanation of the selection of appropriate surgical and chemotherapeutic options are provided throughout the case discussion.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Treatment Reviews - Volume 34, Supplement 2, 2008, Pages S8-S11
Journal: Cancer Treatment Reviews - Volume 34, Supplement 2, 2008, Pages S8-S11
نویسندگان
Carmelo Pozzo, Carlo Barone,