کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3987736 1601476 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Remnant liver regeneration after two-stage hepatectomy for multiple bilobar colorectal metastases
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Remnant liver regeneration after two-stage hepatectomy for multiple bilobar colorectal metastases
چکیده انگلیسی

AimsTwo-stage hepatectomy for multiple, bilobar liver metastases from colorectal cancer aimed to minimize liver failure risk by performing the second resection after regeneration, but impact of this strategy on volume of the future liver remnant (FLR) remained to be demonstrated. We compared two-stage hepatectomy with one stage following portal vein embolization (PVE) for multiple, bilobar liver metastases from colorectal cancer as to effects on volume of the FLR.MethodsForty-three patients undergoing major hepatectomy for multiple colorectal cancer metastases were divided retrospectively into patients undergoing hepatectomy following PVE (n = 21) and those undergoing two-stage hepatectomy (n = 22). Increases in FLR volume were compared.ResultsWhile the increase in the volume FLR averaged approximately 70 mL (302.6 mL before PVE vs. 370.9 mL after PVE) and the increase in the ratio of FLR to total liver volume averaged approximately 7.5% (30.2% to 37.5%) following PVE, first-stage hepatectomy increased FLR volume by approximately 100 mL (from 259.4 to 361.4), and the ratio, by 15% (26.9% to 41.6%). The FLR hypertrophy ratio relative to pre-procedure volume estimates in the two-stage group (50.2%) was twice that in the PVE group (25.3%).ConclusionsSuperiority of two-stage hepatectomy in hypertrophy of the FLR was confirmed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Surgical Oncology (EJSO) - Volume 33, Issue 3, April 2007, Pages 329–335
نویسندگان
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