کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3987885 | 1601477 | 2007 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Long-term prognosis of primary retroperitoneal soft tissue sarcoma Long-term prognosis of primary retroperitoneal soft tissue sarcoma](/preview/png/3987885.png)
AimsTo evaluate the result of treatment and long-term outcome of a population-based cohort of patients with retroperitoneal soft tissue sarcoma (RSTS).MethodsBetween 1 January 1989 and 1 January 1994, 143 patients diagnosed as having primary RSTS were selected from a national pathology database (PALGA) in the Netherlands. In this population-based group of patients, the result of surgery, overall survival (OS) and disease-free survival (DFS) were analysed as well as factors affecting OS and DFS. Median follow-up was 10.2 years.ResultsOperative treatment resulted in a complete tumour resection in 55% of the patients (n = 78), low- and intermediate-grade tumours were more often completely resected than high-grade tumours (P = 0.016). Five- and 10-year cumulative OS was 39% and 21%, respectively, while DFS was 22% and 17%, respectively. In a multivariate analysis low malignancy grade (P = 0.017) and a complete tumour resection (P < 0.001) were associated with better OS.ConclusionsComplete tumour resection and low malignancy grade were independent favourable prognosticators. However, these factors were related too, since surgical success was influenced by malignancy grade.
Journal: European Journal of Surgical Oncology (EJSO) - Volume 33, Issue 2, March 2007, Pages 234–238