کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3987897 1601488 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sentinel lymph node in carcinoma of the anal canal: A review
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Sentinel lymph node in carcinoma of the anal canal: A review
چکیده انگلیسی

AimsTo review the studies investigating the efficacy of the sentinel lymph node (SLN) procedure in anal canal carcinoma and to evaluate its potential role in guiding a more selective approach for patients with the malignancy.MethodsA literature search in the PubMed database was preformed using the key words ‘sentinel lymph node’ and ‘anal cancer’. All indexed original articles (except case reports) on the SLN procedure in cancer of the anal canal were analysed.ResultsThere are five published series to date. Eighty-four patients were studied. Rates of SLN detection and removal ranged from 66 to 100% of patients investigated. Nodal metastases were found in 7.1 to 42% of cases. No serious complications were reported.ConclusionsThe technique has proven to be safe and effective in sampling inguinal SLNs. The detection of occult metastases in clinically unsuspicious nodes represents an important improvement in the process of staging these patients, which has not been possible with any other method of diagnosis. Although SLN procedure is still in an early phase of investigation in this type of cancer, it emerges as an objective method to guide individual therapeutic decisions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Surgical Oncology (EJSO) - Volume 32, Issue 3, April 2006, Pages 247–252
نویسندگان
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