کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3987903 | 1601488 | 2006 | 5 صفحه PDF | دانلود رایگان |
AimTo assess the influence of tumour location on axillary lymph node involvement (ALNI) and prognosis in breast cancer by evaluating the signficance of the sagittal/horizontal alignment.MethodsWe compared 57 patients with superficially located breast carcinomas up to 3.0 cm with patients having lesions in posterior planes of the breast. Both groups were matched according to age, time of diagnosis, tumour size, grade, hormonal receptor status and tumour site within the frontal plane. Histologic evidence of skin involvement, excluding tumours fulfilling the criteria for pT4b, was defined as inclusion criteria and reference plane for superficial tumour location.ResultsTumours situated in the superficial region of the breast, compared to those located in deeper planes, have an increased risk of ALNI (p=0.023), whereas no difference was observed with reference to disease-specific survival (p=0.203).ConclusionThis study shows that ALNI is dependent on sagittal/horizontal as well as frontal tumour location. Clinicians should be aware that tumours lying posteriorly may be at increased risk of occult spread outside axillary lymph nodes.
Journal: European Journal of Surgical Oncology (EJSO) - Volume 32, Issue 3, April 2006, Pages 287–291