کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3988431 1601484 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The prognostic impact of the extent of lymph node dissection in patients with stage III melanoma
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
The prognostic impact of the extent of lymph node dissection in patients with stage III melanoma
چکیده انگلیسی

AimsTo analyse disease-free and overall survival in 67 melanoma patients who underwent dissection for clinically apparent regional lymph node metastases, taking into account the total number of excised lymph nodes.MethodsAfter a median follow-up time of 16 months, 47 recurrences were observed and 43 patients died. The median disease-free and overall survival intervals were 14 and 24 months respectively.ResultsMultivariate analyses revealed that the number of excised lymph nodes had a significant impact on overall survival (P = 0.036) but not on disease-free survival (P = 0.97). Extranodal growth was the only statistically significant prognostic factor both for disease-free (P = 0.005) and overall (P = 0.038) survival. Age, nodal basin, primary tumor ulceration, tumor thickness and number of positive lymph nodes were not significant prognostic factors.ConclusionsOur results suggest that the total number of lymph nodes excised in the dissection has impact on overall survival of stage III melanoma patients and should be considered in clinical assays.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Surgical Oncology (EJSO) - Volume 32, Issue 7, September 2006, Pages 790–794
نویسندگان
, , , , , , , ,