کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3989054 | 1258615 | 2012 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Pancreaticoduodenectomy in a tertiary referral center in Saudi Arabia: A retrospective case series Pancreaticoduodenectomy in a tertiary referral center in Saudi Arabia: A retrospective case series](/preview/png/3989054.png)
ContextPerioperative outcome of pancreaticoduodenectomy is related to work load volume and to whether the procedure is carried out in a tertiary specialized hepato-pancreatico-biliary (HPB) unit.ObjectiveTo evaluate the perioperative outcome associated with pancreaticoduodenectomy in a newly established HPB unit.PatientsAnalysis of 32 patients who underwent pancreaticoduodenectomy (PD) for benign and malignant indications.DesignRetrospective collection of data on preoperative, intraoperative and postoperative care of all patients undergoing PD.ResultsThirty-two patients (16 male and 16 female) with a mean age of 59.5 ± 12.7 years were analyzed. The overall morbidity rate was high at 53%. The most common complication was wound infection (n = 11; 34.4%). Pancreatic and biliary leaks were seen in 5 (15.6%) and 2 (6.2%) cases, respectively, while delayed gastric emptying was recorded in 7 (21.9%). The female sex was not associated with increased morbidity. Presence of co-morbid illness, pylorus-preserving PD, intra-operative blood loss ⩾1 L, and perioperative blood transfusion were not associated with significantly increased morbidity. The overall hospital mortality was 3.1% and the cumulative overall (OS) and disease free survival (DFS) at 1 year were 80% and 82.3%, respectively. The cumulative overall survival for pancreatic cancer vs ampullary tumor at 1 year were 52% vs 80%, respectively.ConclusionPD is associated with a low risk of operative death when performed by specialized HPB surgeons even in a tertiary referral hospital. However, the postoperative morbidity rate remains high, mostly due to wound infection. Further improvement by reducing postoperative infection may help curtail the high postoperative morbidity.
Journal: Journal of the Egyptian National Cancer Institute - Volume 24, Issue 1, March 2012, Pages 47–54