کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3989096 | 1258620 | 2013 | 4 صفحه PDF | دانلود رایگان |
ObjectiveTo investigate the causes of groin recurrence in patients with vulval cancer who previously had negative nodes following superficial inguinal node dissection (SIND).Material and methodsForty-one patients with squamous cell carcinoma of the vulva (stage I or II) were operated upon. The primary treatment was wide local excision with 2 cm safety margin and superficial inguinal lymphadenectomy. Six patients had ipsilateral and one patient had bilateral groin recurrence. Those patients were subjected to deep inguinal node dissection (one patient required bilateral node dissection).ResultsThe mean age at time of diagnosis was 59 years (range 51–68). The median follow-up period for all patients was 63 months (range 24–71) and that of the recurrent cases was 20 months (range 12–38). The mean depth of invasion of the recurrent cases was 5.5 mm (range 5–5.9 mm) and the mean diameter of the primary tumor in recurrent cases was 3.8 cm (range 3–4.5 cm). All recurrent cases had a high grade of the primary tumor. The median interval to recurrence was 21 months (range 12–57). The groin recurrence rate after negative SIND was 17% (7/41 patients).The mean number of nodes resected per groin was eight (range 1–17). The nodes ranged in size from 0.2 to 4.0 cm.ConclusionCarcinoma of the vulva with the following criteria (size of tumor is greater than 3 cm, depth of invasion greater than 5 mm, and high grade tumors) is at high risk of recurrence.
Journal: Journal of the Egyptian National Cancer Institute - Volume 25, Issue 3, September 2013, Pages 121–124