کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3997869 | 1601705 | 2011 | 5 صفحه PDF | دانلود رایگان |
BackgroundVascular encasement of major vessels has been introduced as element of image defined risk factors (IDRF) for stratification of abdominal neuroblastoma. Some subgroups of this tumor entity are still subject of discussion regarding surgical approach and radicality. Aim of this study was to analyse a cohort of related patients.Patients and methodsChildren operated on for neuroblastoma with encasement of major abdominal vessels (April 2002–April 2009) were retrospectively evaluated regarding surgical procedures, intra- and postoperative complications, and outcome.ResultsThere were 18 patients with abdominal NB and encasement of major vessels. Mean age at operation was 43.5 months (2.5–113), mean operation time was 228 minutes (157–428). Complete macroscopic tumor resection was realised in 14 children. Vascular reconstruction was necessary in 5 patients. Tumor progression/relapses requiring further operation occurred in 3 patients. Major postoperative complications were 1 loss of unilateral renal function with subsequent nephrectomy, 1 renal vein thrombosis (operative revision), 1 renal artery embolism (operative revision), and 1 ureteral obstruction (stenting). Mean follow up was 34.8 months (2–78).ConclusionsVascular encasement as part of IDRF is a valuable tool for stratification of abdominal NB. Surgery of NB with vascular encasement includes divers and complex procedures. Children seem to benefit from complete tumor resection or at least relevant tumor reduction although operations can mean a relevant strain for the patients.
Journal: Surgical Oncology - Volume 20, Issue 4, December 2011, Pages 231–235