کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3997880 1259181 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Palliative percutaneous stabilization of lower extremity for bone metastasis using flexible nails and bone cement
ترجمه فارسی عنوان
تثبیت پوستی پایینی اندام تحتانی برای متاستاز استخوان با استفاده از ناخن های انعطاف پذیر و سیمان استخوانی
کلمات کلیدی
ناخن انعطاف پذیر، سیمان اپیلاسیون پوستی، متاستاز استخوان، توموگرافی گسیل پوزیترون، اسکن استخوان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

ObjectivePercutaneous stabilization (PS; percutaneous flexible nailing and intramedullary bone cement injection) was performed at lower extremity long bones in patients with multiple bone metastases with short life expectancy to get mechanical stability and local tumor control. We evaluated the usefulness of PS by clinical status, F-18-FDG PET-CT and bone scintigraphy (BS).MethodsPatients comprised 15 patients (total 20 sites) who had undergone PS for the metastatic bone tumors of lower extremity long bones (femur and tibia). After percutaneous flexible nailing, bone cement was injected (mean amount = 15.5 ± 6.4 ml). Patients' clinical status was evaluated by visual analog scale (VAS). Qualitative assessment of PET-CT and BS was categorized by improved, stable and aggravated states of PS lesion. Quantitative assessment of PET-CT was performed by maximum and mean standardized uptake value (SUVmax and SUVmean).ResultsPS was performed in all of the patients without complication, and showed significant pain improvement of VAS (7.2 ± 0.2 vs. 2.8 ± 0.3, P < 0.001). PS lesion showed improved state in 65% (13/20) and stable state in 35% (7/20). However, naive bony metastatic lesion showed mostly aggravated state in 90% (19/20) in the same patients, which was significantly different compared with PS lesion (P < 0.001). In PS lesion, SUVmax (10.1 ± 6.9 vs. 7.1 ± 5.2, P = 0.008) and SUVmean (6.2 ± 4.8 vs. 4.6 ± 3.7, P = 0.008) showed significantly decreased uptake after PS.ConclusionBy PS in lower extremity long bones, patients can reduce regional pain, and has the possibility of local tumor control. PS can be performed for lower extremity bone metastasis in poor general condition to perform conventional intramedullary nailing.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Oncology - Volume 23, Issue 4, December 2014, Pages 192–198
نویسندگان
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