کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3998993 | 1601776 | 2008 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Management of Melanoma: A European Perspective
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Clinical management of melanoma requires insight into the utility of adjuvant surgical and systemic therapy options. This article discusses the evidence from randomized, controlled trials of adjuvant surgical therapy, sentinel node biopsy, and surveillance of regional lymph node basins by ultrasound. Ultrasound also can be used to identify metastasis in the sentinel node to avoid unnecessary sentinel node biopsies. It describes the experience with chemotherapy, immunostimulants, and vaccines, which have failed as adjuvants in stage II–III disease. Interferon has a consistent effect on relapse-free survival, although it does not have a significant benefit for overall survival.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Oncology Clinics of North America - Volume 17, Issue 3, July 2008, Pages 635–648
Journal: Surgical Oncology Clinics of North America - Volume 17, Issue 3, July 2008, Pages 635–648
نویسندگان
Alexander M.M. Eggermont, Christiane Voit,