کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4000102 1259366 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Accuracy of high resolution (1.5 tesla) pelvic phased array magnetic resonance imaging (MRI) in staging prostate cancer in candidates for radical prostatectomy: Results from a prospective study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Accuracy of high resolution (1.5 tesla) pelvic phased array magnetic resonance imaging (MRI) in staging prostate cancer in candidates for radical prostatectomy: Results from a prospective study
چکیده انگلیسی

ObjectiveTo evaluate the role of pelvic phased array MRI in staging prostate cancer (CaP).Materials and methodsWe prospectively collected data over 12 months on CaP patients who underwent preoperative MR imaging with a pelvic phased array before radical prostatectomy. MR images were analyzed prospectively by 2 radiologists. MR imaging findings were then correlated with pathologic findings.ResultsOverall, 101 patients were included with a mean PSA level of 8 (range 1.8–30). Reader 1 (AUC 0.895, 95% CI 0.791–0.999) had a higher performance than reader 2 (AUC 0.687, 95% CI, 0.555–0.819) and than DRE (AUC 0.728, 95% CI, 0.599–0.857) in discriminating T2 from T3 CaP (P = 0.01). The κ-index of inter-observer agreement was 0.56. A model that combines MRI findings, DRE, PSA, and Gleason score was the most competitive for staging (AUC 0.895, 95% CI, 0.791–0.999). For the multivariate analysis, 3 criteria were significantly associated with extracapsular extension: asymmetry of the neuro-vascular bundles (P = 0.001), asymmetric enhancement of neurovascular bundles (P = 0.02), and bulging of the capsule (P = 0.0003).ConclusionPelvic phased array MRI presented satisfying results in its ability to adequately stage CaP and notably in detecting the extracapsular extension of tumors. It is likely to provide reliable information but rather in the hands of an experienced radiologist.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Urologic Oncology: Seminars and Original Investigations - Volume 31, Issue 4, May 2013, Pages 448–454
نویسندگان
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